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03651cam a2200553Ia 4500 |
| 001 |
828715991 |
| 003 |
OCoLC |
| 005 |
20210116032234.7 |
| 006 |
m o d |
| 007 |
cr cnu---unuuu |
| 008 |
130218s2013 caua ob 001 0 eng |
| 019 |
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|a 829742131
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| 020 |
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|a 9780123946294
|q (electronic bk.)
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| 020 |
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|a 0123946298
|q (electronic bk.)
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|z 9780123942920
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|z 0123942926
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|z (OCoLC)829742131
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| 040 |
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|a AU@
|b eng
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|d IDEBK
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| 049 |
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|a COM6
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| 050 |
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4 |
|a QP601
|b .C733 v.523
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| 072 |
|
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|a SCI
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|2 bisacsh
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| 082 |
0 |
4 |
|a 660.6/3
|2 23
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| 245 |
0 |
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|a Methods in protein design.
|n Volume 523 /
|c edited by Amy E. Keating.
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| 264 |
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1 |
|a San Diego, Calif. :
|b Academic,
|c 2013.
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| 300 |
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|a 1 online resource (xviii, 464 pages) :
|b illustrations.
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| 336 |
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|a text
|b txt
|2 rdacontent.
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| 337 |
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|a computer
|b c
|2 rdamedia.
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| 338 |
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|a online resource
|b cr
|2 rdacarrier.
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| 347 |
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|a data file
|2 rda.
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| 490 |
1 |
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|a Methods in enzymology,
|x 0076-6879 ;
|v v. 523.
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| 504 |
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|a Includes bibliographical references and indexes.
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| 505 |
0 |
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|a Computational design of novel protein binders and experimental affinity maturation -- Mining tertiary structural motifs for assessment of designability -- Computational methods for controlling binding specificity -- Flexible backbone sampling methods to model and design protein alternative conformations -- Osprey: protein design with ensembles, flexibility, and provable algorithms -- Scientific benchmarks for guiding macromolecular energy function improvement -- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins -- Multistate protein design using CLEVER and CLASSY -- Using analyses of amino acid coevolution to understand protein structure and function -- Evolution-based design of proteins -- Protein engineering and stabilization from sequence statistics: variation and covariation analysis -- Enzyme engineering by targeted libraries -- Generation of high-performance binding proteins for pepetide motifs by affinity clamping -- Engineering fibronectin-based binding proteins by yeast surface display -- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing -- Efficient sampling of SCHEMA chimera families to identify useful sequence elements -- Protein switch engineering by domain insertion -- Design of chimeric proteins by combination of subdomain-sized fragments -- [alpha]-helix mimicry with [alpha/beta]-peptides.
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| 588 |
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|a Print version record.
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| 650 |
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|a Protein engineering.
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| 650 |
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7 |
|a SCIENCE
|x Biotechnology.
|2 bisacsh.
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| 650 |
|
7 |
|a Protein engineering.
|2 fast.
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| 655 |
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4 |
|a Electronic books.
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| 700 |
1 |
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|a Keating, Amy E.
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| 710 |
2 |
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|a ScienceDirect (Online service)
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| 830 |
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|a Methods in enzymology ;
|v volume 523.
|x 0076-6879.
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| 907 |
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|1 .i136792236
|u http://ezproxy.coloradomesa.edu/login?url=https://www.sciencedirect.com/science/bookseries/00766879/523
|3 Elsevier
|z Click here for access
|