Current topics in cellular regulation Volume 10 /
Current Topics in Cellular Regulation.
| Other Authors: | Horecker, Bernard L. 1914-, Stadtman, Earl R.,, ScienceDirect (Online service) |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
New York :
Academic Press,
[1976]
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| Physical Description: |
1 online resource. |
| Subjects: |
Table of Contents:
- Front Cover; Current Topics in Cellular Regulation; Copyright Page; Table of Contents; List of Contributors; Preface; Preface to Volume 10; Contents of Previous Volumes; Chapter 1. The Role of Negative Cooperativity and Half-of-the-SitesReactivity in Enzyme Regulation; I. Introduction; II. Theoretical; III. Negatively Cooperative Enzymes-Examples; IV. Mixed Negative-Positive Cooperativity; V. Half-of-the-Sites Reactivity; VI. Enzymes with Half-of-the-Sites Reactivity; VII. Evaluation of Negative Cooperativity and Half-of-the-SitesReactivity.
- VIII. The Biological Significance of Negative CooperativityREFERENCES; Chapter 2. Signal Transfer from Hormone Receptorto Adenylate Cyclase; I. Introduction; II. Hormone-Receptor Interactions; III. Adenylate Cyclase; IV. Coupling between Receptor and Adenylate Cyclase; V. Concluding Remarks; ACKNOWLEDGMENTS; REFERENCES; Addendum; ACKNOWLEDGMENT; REFERENCES FOR ADDENDUM; Chapter 3. Regulation of the Glycogen Phosphorylase System-FromPhysical Measurements to Biological Speculations; I. Introduction; II. The Phosphorylase Cascade System; III. The Individual Components of the Cascade System.
- IV. The MethodsV. Effects of Ligands on Phosphorylase; VI. Heterotropic Interactions of Phosphorylase b; VII. The Relation between Ligand and Probe Binding Sites; VIII. The Phosphorylase b to a Conversion; IX. Protein-Glycogen Complexes-An Approachto the in Vivo Situation; X. The Control of Phosphorylase Activity in Vivo; XI. Conclusion; ACKNOWLEDGMENTS; REFERENCES; Chapter 4. Citrate Synthase; I. Introduction; II. Molecular Properties; III. Ionic Effects; IV. Regulation of Activity-The in Vitro Behavior; V. Regulation of Activity-Approaches to the in Vivo Behavior.
- VI. Chemistry of the Catalytic and Regulatory SitesVII. Concluding Remarks; ACKNOWLEDGMENTS; REFERENCES; Chapter 5. Defects of Glucose-6-phosphate and 6-Phosphogluconate Dehydrogenases in Neurospora and TheirPleiotropic Effects; I. Introduction; II. Mutants; III. Glucose-6-phosphate Dehydrogenase; IV. 6-Phosphogluconate Dehydrogenase; V. Conclusions from Enzyme Studies; VI. Pleiotropic Effects of Pentose Monophosphate Shunt Lesions; VII. Summary; ACKNOWLEDGMENTS; REFERENCES; Chapter 6. Futile Cycles in the Metabolism of Glucose; I. Introduction.
- II. Isotopic Reversibility in the Gluconeogenic PathwayIII. The Fate of Glucose Hydrogens in Glycolysis; IV. Evaluation of Recycling with Tritium-Labeled Glucoses in Liver; V. Metabolism of Labeled Glucose by Rat Liver; VI. Recycling between Pyruvate and Phosphoenol Pyruvate; VII. Recycling of Fructose 6-Phosphate and Thermogenesis; VIII. Occurrence of Other Futile Cycles; IX. Recycling of Glucose in Vivo; X. The Role of Futile Cycles in the Control of Glucose Metabolism; XI. Concluding Remarks; ACKNOWLEDGMENT; REFERENCES; Subject Index.