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| LEADER |
04704cam a2200829Ia 4500 |
| 001 |
795580410 |
| 003 |
OCoLC |
| 005 |
20210116033514.6 |
| 006 |
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| 007 |
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|a OPELS
|b eng
|e pn
|c OPELS
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|d CUS
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| 049 |
|
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|a COM6
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| 050 |
|
4 |
|a QP364.7
|b .G58 1998
|
| 060 |
1 |
0 |
|a W1
|b PR667J v.116 1998
|
| 060 |
1 |
0 |
|a WL 102.8
|b G567 1998
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0 |
4 |
|a The glutamate synapse as a therapeutical target :
|b molecular organization and pathology of the glutamate synapse /
|c edited by O.P. Ottersen, I.A. Langmoen, L. Gjerstad.
|
| 264 |
|
1 |
|a Amsterdam ;
|a New York :
|b Elsevier Science,
|c 1998.
|
| 300 |
|
|
|a 1 online resource (xii, 462 pages) :
|b illustrations.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent.
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia.
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier.
|
| 490 |
1 |
|
|a Progress in brain research,
|x 0079-6123 ;
|v volume 116.
|
| 520 |
|
|
|a This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed. A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation.
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 588 |
0 |
|
|a Online resource; title from publisher's Web site (ScienceDirect, viewed on June 15, 2012).
|
| 505 |
0 |
|
|a Machine derived contents note: I. Glutamate Release and Transport. -- II. Glutamate Synthesis and Translocation to Vesicles. -- III. Glutamate Receptors. -- IV. Glutamate Toxicity and Cell Death in the Cental Nervous System. -- V. Conditions of Perturbed Glutamatergic Transmission. -- VI. Perspectives.
|
| 506 |
|
|
|a Online full text access is restricted to licensed organisations.
|
| 546 |
|
|
|a English.
|
| 650 |
|
0 |
|a Glutamic acid
|x Receptors
|x Effect of drugs on.
|
| 650 |
|
0 |
|a Epilepsy
|x Molecular aspects.
|
| 650 |
|
0 |
|a Epilepsy
|x Chemotherapy.
|
| 650 |
|
7 |
|a Epilepsy
|x Chemotherapy.
|2 fast.
|
| 650 |
1 |
2 |
|a Glutamic Acid.
|
| 650 |
1 |
2 |
|a Synaptic Transmission.
|
| 650 |
2 |
2 |
|a Receptors, Glutamate.
|
| 650 |
|
7 |
|a Human Anatomy & Physiology.
|2 hilcc.
|
| 650 |
|
7 |
|a Health & Biological Sciences.
|2 hilcc.
|
| 650 |
|
7 |
|a Neuroscience.
|2 hilcc.
|
| 650 |
|
6 |
|a Glutamique, Acide
|x Récepteurs, Effets des médicaments sur les.
|
| 650 |
|
6 |
|a Épilepsie
|x Aspect moléculaire.
|
| 650 |
|
6 |
|a Épilepsie
|x Chimiothérapie.
|
| 655 |
|
4 |
|a Electronic books.
|
| 700 |
1 |
|
|a Ottersen, O. P.
|q (Ole P.),
|e editor.
|
| 700 |
1 |
|
|a Langmoen, Iver Arne,
|e editor.
|
| 700 |
1 |
|
|a Gjerstad, L.
|q (Leif),
|e editor.
|
| 710 |
2 |
|
|a ScienceDirect (Online service)
|
| 773 |
0 |
|
|t Progress in brain research
|g no:116
|x 0079-6123.
|
| 776 |
0 |
8 |
|i Print version:
|t Glutamate synapse as a therapeutical target.
|d Amsterdam ; New York : Elsevier, 1998
|z 0444827544
|w (DLC) 98029333
|w (OCoLC)39465432.
|
| 830 |
|
0 |
|a Progress in brain research ;
|v v. 116.
|
| 907 |
|
|
|a .b63838540
|b multi
|c -
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|
|a MARCIVE Comprehensive, in 2023.02
|
| 948 |
|
|
|a MARCIVE Over, 04/2021
|
| 994 |
|
|
|a 92
|b COM
|
| 995 |
|
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|a Loaded with m2btab.ltiac in 2023.02
|
| 995 |
|
|
|a Loaded with m2btab.ltiac in 2021.04
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| 995 |
|
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|u http://ezproxy.coloradomesa.edu/login?url=https://www.sciencedirect.com/science/bookseries/00796123/116
|3 Elsevier
|z Click here for access
|