The Flaviviruses Pathogenesis and Immunity /

Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a g...

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Other Authors: Chambers, Thomas J.,, Monath, Thomas P.,, ScienceDirect (Online service)
Format: eBook
Language: English
Published: Amsterdam ; London : Elsevier, 2003.
Physical Description: 1 online resource (xiv, 486 pages, 18 unnumbered pages of plates) : illustrations (some color).
Series: Advances in virus research ; v. 60.
Subjects:
Summary: Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts. Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions. New, detailed information on the pathogenesis and immunology of the Flavivirus family. Descibes the technologies that have contributed to our current knowledge about the Flaviviruses. Identifies the major problems faced in attempting to further understand the virus-host interactions that result in disease. An exhaustive compendium of current and past knowledge on the Flavivirus family.
Item Description: Includes bibliographical references and index.
Chapter 1. Molecular Determinants of Virulence: The Structural and Functional Basis for Flavivirus Attenuation --Chapter 2. Genetic Resistance to Flaviviruses -- Chapter 3. Immunobiology of Mosquito-Borne Encephalitic Flaviviruses -- Chapter 4. Immune Modulation by Flaviviruses -- Chapter 5. Mechanisms of DengueVirus-Induced Cell Death --Chapter 6. Dynamics Flavivirus Infection in Mosquitoes --Chapter 7. Dynamics of Infection in Tick Vectors and at the Tick-Host Interface -- Chapter 8. Pathogenesis of Flavivirus Encephalitis -- Chapter 9. Pathogenesis and Pathophysiology of Yellow Fever -- Chapter 10. Immunology and Immunopathogenesis of Dengue Disease -- Chapter 11. Neutralization and Antibody-Dependent Enhancement of DengueViruses.
Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts. Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions. New, detailed information on the pathogenesis and immunology of the Flavivirus family. Descibes the technologies that have contributed to our current knowledge about the Flaviviruses. Identifies the major problems faced in attempting to further understand the virus-host interactions that result in disease. An exhaustive compendium of current and past knowledge on the Flavivirus family.
Text in English.
Physical Description: 1 online resource (xiv, 486 pages, 18 unnumbered pages of plates) : illustrations (some color).
Bibliography: Includes bibliographical references and index.
ISBN: 0080493823
9780080493824
0120398605
9780120398607