Advances in immunology Volume 55

From the Reviews of Previous Volumes "Provides unrivalled value in both academic and fiscal terms and should be purchased by hard pressed librarians as a major priority to be jealously defended."--JOURNAL OF MEDICAL MICROBIOLOGY "Advances in Immunology must find itself among the most...

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Other Authors: Dixon, Frank J. 1920-2008,, ScienceDirect (Online service)
Format: Electronic
Language: English
Published: San Diego ; New York ; Boston : Academic Press, [1994]
Physical Description: 1 online resource (viii, 455 pages) : illustrations.
Series: Advances in immunology.
Subjects:
Table of Contents:
  • Front Cover; Advances in Immunology, Volume 55; Copyright Page; Contents; Chapter 1. The kit Ligand, Stem Cell Factor; I. Introduction; II. The Stem Cell Factor Receptor, Encoded by the c-kit Gene; III. The kit Ligand, Stem Cell Factor; IV. Tissue Distribution of SCF and the SCF Receptor; V. Nature and Biological Consequences of Mutations Affecting SCF or the SCF Receptor; VI. Regulation of Expression of SCF and the SCF Receptor; VII. Signal Transduction through the SCF Receptor; VIII. Biological Consequences of Interactions between the SCF Receptor and Its Ligand; IX. Lymphohematopoiesis.
  • X. Mast Cell BiologyXI. Melanocyte Biology; XII. Germ Cell Development; XIII. The Nervous System; XIV. Neoplasia; XV. SCF as a Therapeutic Agent; XVI. Concluding Remarks; References; Chapter 2. Interleukin-8 and Related Chemotactic Cytokines-CXC and CC Chemokines; I. Introduction; II. Structures and Chemical Properties; III. Chemokine Genes; IV. Cellular Sources of CXC and CC Proteins; V. Biological Activities; VI. Receptors; VII. Signal Transduction; VIII. Role in Pathology; References; Chapter 3. Receptors for Transforming Growth Factor-ß; I. Introduction.
  • II. Structure and Activity of Members of the TGF-ß SuperfamilyIII. Serine/Threonine Kinase Receptors; IV. Other TGF-ß Receptors; V. Signal Transduction by TGF-ß; VI . Perspectives; References; Chapter 4. Biochemistry of B Lymphocyte Activation; I. Introduction; II. Different Models of B Cell Activation; III. Structure of the B Cell Antigen Receptor; IV. Initial Signaling Reactions Stimulated by the B Cell Antigen Receptor; V. Early Cellular Events Following Antigen Contact; VI. Mechanism of Contact-Dependent T Cell Help.
  • VII. Signaling by Receptors for B Cell Growth and Differentiation FactorsVIII. B Cell Survival; IX. Summary; References; Chapter 5. CD5 B Cells, a Fetal B Cell Lineage; I. Introduction; II. Background; III. Origins of CD5 B Cells; IV. Model for Generation of CD5 B Cells; V. Properties of Murine CD5 B Cells; VI. Biases in Specificity; VII. Biases in V Gene Usage; VIII. A Homologous Human Population?; IX. Final Considerations and Summary; References; Chapter 6. Human Natural Killer Cells: Origin, Clonality, Specificity, and Receptors; I. Introduction; II. Ontogeny of NK Cells.
  • III. Expression of CD3 Genes during NK Cell MaturationIV. Evidence for NK Cell Specificity; V. The Human NK Cell Repertoire; VI. Genetic Analysis of Human NK-Defined Allospecificities; VII. Involvement of Class I Molecules in NK-Specific Functions; VIII. Clonally Distributed Molecules (p58) Involved in Regulation of NK-Mediated Cytolysis; IX. p58 Molecules as Putative Receptors for MHC Class I Molecules in Human NK Cells; X. Human NK Receptors for Class I Molecules Are Composed of p58 Dimers; XI. Effect of p58 Modulation on Cytolytic Activity.