Advances in cancer research Volume 80 /
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented on a variety of topics including platelet-derived growth factor in disease, genetic predisposition in tumor developmen...
| Other Authors: | Vande Woude, George F., Klein, George, 1928-1981., ScienceDirect (Online service) |
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| Format: | eBook |
| Language: | English |
| Published: |
San Diego, Calif. :
Academic Press,
[2001]
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| Physical Description: |
1 online resource. |
| Series: |
Advances in cancer research ;
v. 80. |
| Subjects: |
| Summary: |
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented on a variety of topics including platelet-derived growth factor in disease, genetic predisposition in tumor development, primary effusion lymphoma, and many more. Key Features* Involvement of Platelet-Derived Growth Factor in Disease: Development of Specific Antagonists* Tumor Suppression Activity of Adenovirus E1a Protein: Anoikis and the Epithelial Phenotype* Comparative Analysis of the Transforming Mechanisms of. |
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| Item Description: |
Title from PDF title page (viewed Sep. 27, 2007). Includes bibliographical references and index. Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented on a variety of topics including platelet-derived growth factor in disease, genetic predisposition in tumor development, primary effusion lymphoma, and many more. Key Features* Involvement of Platelet-Derived Growth Factor in Disease: Development of Specific Antagonists* Tumor Suppression Activity of Adenovirus E1a Protein: Anoikis and the Epithelial Phenotype* Comparative Analysis of the Transforming Mechanisms of. Front Cover; Advances in Cancer Research; Copyright Page; Contents; Contributors to Volume 80; Chapter 1. Involvement of Platelet-Derived Growth Factor in Disease: Development of Specific Antagonists; I. Introduction; II. Platelet-Derived Growth Factor (PDGF) and PDGF Receptors; III. Intracellular Signal Transduction; IV. In Vivo Function of Pdgf; V. Pdgf in Disease; VI. Pdgf and Pdgf Receptors as Drug Targets; VII. Future Perspectives; References; Chapter 2. Tumor Suppression Activity of Adenovirus E1a Protein: Anoikis and the Epithelial Phenotype; I. Introduction. II. Historical Development of E1a as a Tumor SuppressorIII. Epithelial Conversion: Phenomenology; IV. Epithelial Conversion: Mechanisms; V. Anoikis Sensitization and Tumor Suppression by E1a; References; Chapter 3. Comparative Analysis of the Transforming Mechanisms of Epstein-Barr Virus, Kaposi's Sarcoma-Associated Herpesvirus, and Herpesvirus Saimiri; I. Introduction; II. Comparative Analysis of Gamma Herpesvirus Gene Products; III. Conclusion; References; Chapter 4. Genetic Predisposition and Somatic Diversification in Tumor Development and Progression; I. Introduction. II. Hereditary Colorectal Cancer SyndromesIII. Tumor Mutations and Molecular Clocks: Gateways to the Fourth Dimension; References; Chapter 5. Primary Effusion Lymphoma: A Liquid Phase Lymphoma of Fluid-Filled Body Cavities; I. Definition of Primary Effusion Lymphoma; II. Histogenes of Primary Effusion Lymphoma; III. Pathogenesis of Primary Effusion Lymphoma; IV. Epidemiology of Primary Effusion Lymphoma; V. Clinical Features of Primary Effusion Lymphoma; VI. Radioimaging of Primary Effusion Lymphoma; VII. Differential Diagnosis of Primary Effusion Lymphoma. VIII. Therapy of Primary Effusion LymphomaIX. Perspectives; References; Chapter 6. Dimensions of Antigen Recognition and Levels of Immunological Specificity; I. Introduction; II. Logical Preliminaries: Boundaries of Categories and Categories of Boundaries; III. Monovalent Recognition; IV. Multivalent Recognition; V. Specificity of Cellular Activation; VI. Organismal Specificity; VII. Conclusions; References; Chapter 7. Topoisomerase I-Mediated DNA Damage; I. Introduction; II. Structural Domains of Top1; III. Top1 Functions and Protein Interactions. IV. The Top1 Catalytic Cycle and Cleavage ComplexesV. Anticancer Top1 Poisons; VI. Suppression and/or Enhancement of Top1 Cleavage Complexes by DNA Damage; VII. Processing of Top1-Mediated Dna Lesions; VIII. Conclusions; References; Index. |
| Physical Description: |
1 online resource. |
| Bibliography: |
Includes bibliographical references and index. |
| ISBN: |
9780080524382 0080524389 0120066807 9780120066803 |