Pharmaceuticals from microbes the bioengineering perspective /
This book has been assembled with the hope of being an authoritative, comprehensive, conceptually sound and highly informative compilation of recent advances describing the concepts of bioengineering in the field of microbiology. It comprises of seven chapters written by eminent authors in their res...
| Other Authors: | Arora, Divya, 1981-, Sharma, Chetan (Of the Guru Angad Dev Veterinary and Animal Science University),, Jaglan, Sundeep,, Lichtfouse, Eric,, SpringerLink (Online service) |
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| Format: | eBook |
| Language: | English |
| Published: |
Cham, Switzerland :
Springer,
2019.
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| Physical Description: |
1 online resource (xii, 212 pages) : illustrations (some color). |
| Series: |
Environmental chemistry for a sustainable world.
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| Subjects: |
Table of Contents:
- Intro; Preface; Contents; Contributors; About the Editors; Chapter 1: Advances in Drug Delivery Strategies for Microbial Healthcare Products; 1.1 Introduction; 1.2 Anti-inflammatory and Immunosuppressant Drugs; 1.2.1 Cyclosporine A; 1.2.2 Tacrolimus; 1.3 Cardiovascular Protective Drugs; 1.3.1 Lovastatin; 1.3.2 Simvastatin; 1.4 Antitumoral Drugs; 1.4.1 Aclarubicin; 1.4.2 Bleomycin; 1.4.3 Doxorubicin; 1.4.4 Mithramycin; 1.4.5 Mitomycin C; 1.4.6 Paclitaxel; 1.4.7 Prodigiosin; 1.5 Antibiotic Drugs; 1.5.1 Amphotericin B; 1.5.2 Gentamicin; 1.5.3 Polymyxin B; 1.5.4 Nisin; 1.5.5 Vancomycin.
- 1.6 Probiotic Microorganisms1.7 Conclusion; References; Chapter 2: Live-Attenuated Bacterial Vectors for Delivery of Mucosal Vaccines, DNA Vaccines, and Cancer Immunotherapy; 2.1 Introduction; 2.2 Desired Features of Live-Attenuated Bacterial Vectors; 2.2.1 Attenuation; 2.2.2 Plasmid Maintenance; 2.3 Immune Mechanisms of Vaccines Delivered by Live-Attenuated Bacterial Vectors; 2.4 Delivery of DNA Vaccines by Live-Attenuated Bacterial Vectors; 2.5 Immunotherapy Against Cancer Using Live-Attenuated Bacterial Vectors; 2.6 Novel Technologies for Tailored and Enhanced Immune Response.
- 2.6.1 Control of Gene Expression: Use of Plasmid Copy Number and In Vivo Promoters2.6.2 Acid Resistance; 2.6.3 Detoxification of Lipopolysaccharide; 2.6.4 Optimization of Virulence: Control of Safety and Immunogenicity; 2.6.5 Cytosolic Delivery of Antigen; 2.7 Conclusion; References; Chapter 3: Poly-lactide/Poly-lactide-co-glycolide-Based Delivery System for Bioactive Compounds Against Microbes; 3.1 Introduction; 3.2 Preparation of Poly-lactide/Poly-lactide-co-glycolide Particles; 3.3 Different Facets of an Interaction of the Polymeric Particles with the Cells.
- 3.4 Poly-lactide/Poly-lactide-co-glycolide Particulate Delivery System of Bioactive Therapeutics3.4.1 Nanoparticle-Based Delivery System; 3.4.2 Microparticle Delivery System; 3.4.3 Nanoparticle/Microparticle Delivery System; 3.4.4 Biodegradable Polymeric Scaffold; 3.5 Conclusion; References; Chapter 4: Drug Delivery Systems Based on Pullulan Polysaccharides and Their Derivatives; 4.1 Introduction; 4.2 Pullulan-Based Systems with Antibacterial or Antifungal Activity; 4.3 Pullulan-Based Systems with Antitumor Properties.
- 4.4 Pullulan-Based Systems with Antioxidant Activity and Free Radical Scavenging Properties4.5 Pullulan-Based Systems with Anti-inflammatory and Immunomodulatory Properties; 4.6 Pullulan-Based Systems with Antilipidemic and Antiglycemic Properties; 4.7 Pullulan-Based Systems for Heart Diseases; 4.8 Pullulan-Based Systems for Bone Diseases; 4.9 Conclusions and Future Remarks; References; Chapter 5: Microbial Modifications of Flavonols; 5.1 Introduction; 5.2 Significance of Flavonol and Their Microbial Modified Derivatives; 5.3 Current Approaches for Microbial Flavonol Modifications.