Advances in nanomedicine for the delivery of therapeutic nucleic acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs)ïÅ1/2using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies ada...

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Other Authors: Nimesh, Surendra,, Chan, Ramesh,, Gupta, Nidhi (Research scientist),, ScienceDirect (Online service)
Format: eBook
Language: English
Published: Duxford : Woodhead Publishing, [2017]
Physical Description: 1 online resource.
Series: Woodhead Publishing series in biomedicine.
Subjects:
Table of Contents:
  • 1. Nanomedicine for delivery of therapeutic molecules
  • 2. Nanoparticles as nucleic acid delivery vectors
  • 3. Methods for charactericzation of nanoparticles
  • 4. Nanoparticles for DNA delivery
  • 5. Nanoparticles for siRNA-mediated gene silencing
  • 6. Nanoparticles for locked nucleic acid delivery
  • 7. Nanoparticles for ribozymes delivery
  • 8. Nanoparticles for DNAzymes delivery
  • 9. Pharmacokinetics and biodistribution of the nanoparticles
  • 10. Nanotoxicology: evaluation of toxicity potential of nanoparticles
  • 11. Regulatory aspects of nanoparticulate mediated nucleic acid delivery systems
  • 12. Clinical studies and future prospects
  • Index.