Perspectives in environmental toxicology
This book is a valuable contribution to the debate about the harmful effects of environmental toxicants on human health, which is a growing concern in the 21st century. Complementary chapters decipher the phenomena and highlight the latest developments in environmental toxicology, providing readers...
| Other Authors: | Kesari, Kavin Kumar,, SpringerLink (Online service) |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Cham, Switzerland :
Springer,
2017.
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| Physical Description: |
1 online resource (xii, 214 pages) : illustrations (some color). |
| Series: |
Environmental science and engineering (Springer (Firm)). Environmental science.
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| Subjects: |
Table of Contents:
- Foreword; Preface and Acknowledgements; Contents; 1 Neurophysiological and Behavioral Dysfunctions After Electromagnetic Field Exposure: A Dose Response Relationship; Abstract; 1 Introduction; 1.1 History and Sources of Electromagnetic Fields; 1.2 EMF Exposure and Dosimetry; 2 Biomarkers of Neurological Dysfunction; 2.1 Protein Kinase C (PKC); 2.2 Micronuclei: Genomic Instability; 2.3 The Mitochondrial Pathway: Role in Apoptosis; 2.4 Antioxidant Enzymes; 2.5 Melatonin and Calcium Ion Concentration; 3 Effects of RF-EMF on Developing CNS; 3.1 Effects of EMF Exposure on Behavior and Cognition.
- 3.2 Effects of EMF on Neurotransmitters3.3 Histopathological Alterations in Brain Induced by EMF; 4 EMF Links to Alzheimer Disease; 5 Exposure Response Relationship; 5.1 Experimental Data Evaluation; 6 Conclusion; References; 2 LPO and ROS Production in Rat Brain Exposed to Microwaves: Computational Elucidation of Melatonin in Repair System; Abstract; 1 Introduction; 2 Methodology; 2.1 Animal Exposure; 2.2 Exposure Chamber; 2.3 Lipid Peroxidation (LPO) Assay; 2.4 Reactive Oxygen Species (ROS); 2.5 Preparation of Drug Enzymes 3D Structures; 2.6 Molecular Interaction Analysis.
- 2.7 Statistical Analysis3 Results; 3.1 Lipid Peroxidation; 3.2 Reactive Oxygen Species (ROS); 3.3 In Silico Docking (AChE and BuChE); 4 Discussion; 5 Conclusion; References; 3 Nanoparticles: Applications, Toxicology and Safety Aspects; Abstract; 1 Introduction to Nanoparticles; 1.1 Sources of Nanoparticles; 1.2 Classification of Nanoparticles; 2 Applications of Nanoparticles; 3 Production and Exposure of Nanoparticles; 4 Carbon Based Nanoparticles and Their Toxicity; 5 Fullerenes and Its Toxicity; 6 Engineered Nanoparticle; 7 Handling of Nanoparticles; 8 Guidelines/Regulatory Measures.
- 9 Factors Affecting Exposure10 Work Practices; 11 Personal Protective Equipment; 11.1 Protective Gloves; 11.2 Eye Protection; 11.3 Protective Clothing; 11.4 Respiratory Protection; References; 4 Cadmium Toxicity Showing Organ Specific Signature of Responsiveness; Abstract; 1 Introduction; 1.1 Environment and Metal Ions; 1.2 Environmental Metal Toxicity and Health; 1.3 Metal Ion, Reactive Oxygen Species (ROS) and Disease; 2 Cadmium: A Contaminant in Environment; 2.1 General Standard; 2.2 Industry Specific Standards; 2.3 Food Contaminant; 2.4 Water Contaminant; 2.5 Cadmium and Health.
- 3 Correlation Between Cadmium and ROS3.1 An Intermediate Pathogenesis: ROS Generation by Metal Toxicity; 3.2 Antioxidant Enzyme and Diseases: Reaction of Toxic Metal; 3.3 Role of Mitochondria and ROS in Cellular Pathogenesis of Metal Toxicity; 4 Stress Signaling and Apoptosis: Relation to Metal Toxicity; 4.1 p53 Mechanistic Role in Stress Signalling; 4.2 Mitogen-Activated Protein Kinases (MAPKs) Signaling in Metal Induced Stress; 5 Conclusion and Future Recommendations; References.