Manipulation and characterization of electrosprayed ions under ambient conditions methods and instrumentation /
This thesis addresses the evolving field of measurement science, specifically that of mass spectrometry (MS) and ion mobility spectrometry (IMS) based techniques. It focuses on the design, construction and implementation of low-cost, easy-to-manufacture measurement tools that are used in modern sett...
| Main Author: | Baird, Zane. |
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| Other Authors: | SpringerLink (Online service) |
| Format: | eBook |
| Language: | English |
| Published: |
Cham :
Springer,
2017.
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| Physical Description: |
1 online resource. |
| Series: |
Springer theses.
|
| Subjects: |
| Summary: |
This thesis addresses the evolving field of measurement science, specifically that of mass spectrometry (MS) and ion mobility spectrometry (IMS) based techniques. It focuses on the design, construction and implementation of low-cost, easy-to-manufacture measurement tools that are used in modern settings such as airport security screening. Advances in these technologies often involve minimal performance enhancement at ever-increasing cost, which in turn limits accessibility to versatile measurement tools. This problem is addressed using desktop 3D printers along with widely available materials for the production of novel ion lenses and an IMS instrument with a performance comparable to that of many commercial systems. Bairdś findings are a source of inspiration for scientists exploring this emerging field. |
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| Item Description: |
"Doctoral thesis accepted by Purdue University, West Lafayette, USA." Includes bibliographical references. Supervisor's Foreword; Parts of this thesis have been published in the following journal articles:; Acknowledgements; Contents; List of Figures; 1 Introduction; 1.1 Overview; 1.2 Electrospray Ionization; 1.2.1 A Brief History; 1.2.2 Electrospray Ion Formation; 1.2.3 Preparative Electrospray; 1.3 Simulations of Ion Motion at Atmospheric Pressure; 1.4 Fused Deposition Modeling; References; 2 Ion Transport and Focal Properties of an Ellipsoidal Electrode Operated at Atmospheric Pressure; 2.1 Introduction; 2.2 Experimental; 2.2.1 Chemicals and Instrumentation. 2.2.2 Ion Transport and Beam Profiling2.2.3 Ion Transport Efficiency; 2.2.4 Ion Trajectory Simulation; 2.2.5 Mass Spectrometer Interface; 2.3 Results and Discussion; 2.3.1 Focusing of Electrosprayed Ions; 2.3.2 Simulated Ion Trajectories; 2.3.3 Ion Transport Efficiency; 2.3.4 Mass Spectrometer Interface; 2.4 Conclusions; References; 3 Ion Manipulation in Air Using a System of Curved 3D Printed Plastic Electrodes; 3.1 Introduction; 3.2 Experimental; 3.2.1 Production and Focusing of Ions in Air; 3.2.2 Simulations of Ion Motion; 3.2.3 Imaging of Focused Ion Stream; 3.2.4 Ion Transfer Efficiency. 3.2.5 Ion/Molecule Reactions3.2.6 Separation of Ions in Air; 3.3 Results and Discussion; 3.3.1 Ambient Ion Focusing; 3.3.2 Ion Transfer Efficiency; 3.3.3 Ion/Molecule Reactions; 3.3.4 Separation of Ions in Air; 3.4 Conclusions; References; 4 3D Printed Annular Focusing Ambient Ion Mobility Spectrometer; 4.1 Introduction; 4.2 Experimental; 4.2.1 Ion Trajectory Simulations; 4.2.2 Device Design and Construction; 4.2.2.1 Description of Device; 4.2.2.2 3D Printed Components; 4.2.2.3 Electronics; 4.2.2.4 Operational Parameters of 3D Printed IMS; 4.2.3 Ion Deposition Image Collection. 4.2.4 Ion Transmission Efficiency4.3 Results and Discussion; 4.3.1 Annular Ion Focusing; 4.3.2 Annularly Focused Ion Mobility Spectrometer; 4.3.3 Ion Transmission Efficiency; 4.4 Conclusions; References; 5 Outlook and Future Directions; 5.1 3D Printing in the Scientific Laboratory; 5.1.1 Overview of FDM Printers and Components; 5.1.2 Notable Applications of FDM; 5.2 Ion Focusing at Atmospheric Pressure; 5.3 Ambient Ion Mobility Spectrometry; References; Curriculum Vitae. This thesis addresses the evolving field of measurement science, specifically that of mass spectrometry (MS) and ion mobility spectrometry (IMS) based techniques. It focuses on the design, construction and implementation of low-cost, easy-to-manufacture measurement tools that are used in modern settings such as airport security screening. Advances in these technologies often involve minimal performance enhancement at ever-increasing cost, which in turn limits accessibility to versatile measurement tools. This problem is addressed using desktop 3D printers along with widely available materials for the production of novel ion lenses and an IMS instrument with a performance comparable to that of many commercial systems. Bairdś findings are a source of inspiration for scientists exploring this emerging field. |
| Physical Description: |
1 online resource. |
| Bibliography: |
Includes bibliographical references. |
| ISBN: |
9783319498690 331949869X |