Bioengineering applications of carbon nanostructures
This book covers the development of biotechnology based on carbon nanostructures, with a focus on nanotubes, addressing also fullerenes and amorphous carbons. The book is divided into 7 chapters, addressing tissue engineering, genetic engineering and therapy, as well as the environmental and health...
| Other Authors: | Jorio, A., SpringerLink (Online service) |
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| Format: | eBook |
| Language: | English |
| Published: |
Cham :
Springer,
[2016]
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| Physical Description: |
1 online resource (x, 163 pages) : illustrations (some color). |
| Series: |
Nanomedicine and nanotoxicology.
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| Subjects: |
| Summary: |
This book covers the development of biotechnology based on carbon nanostructures, with a focus on nanotubes, addressing also fullerenes and amorphous carbons. The book is divided into 7 chapters, addressing tissue engineering, genetic engineering and therapy, as well as the environmental and health impacts of carbon nanostructures. |
|---|---|
| Item Description: |
Includes bibliographical references. This book covers the development of biotechnology based on carbon nanostructures, with a focus on nanotubes, addressing also fullerenes and amorphous carbons. The book is divided into 7 chapters, addressing tissue engineering, genetic engineering and therapy, as well as the environmental and health impacts of carbon nanostructures. Preface; Contents; 1 Bone Repair Utilizing Carbon Nanotubes; Abstract; 1.1 Introduction; 1.2 General Properties of Carbon Nanotubes; 1.3 Bone Tissue and Carbon Nanotubes; 1.4 Application of Carbon Nanotubes in Bone Repair; 1.5 Perspectives on Carbon Nanotubes in Bone Repair; 1.6 Conclusion and Perspectives; References; 2 The Use of Single Wall Carbon Nanotubes as a Delivery System for siRNA; Abstract; 2.1 Introduction; 2.1.1 CNTs as Molecular Transporters; 2.1.2 Application of CNTs as a Delivery System for siRNA; 2.2 Strategies Available for SWCNT Functionalization and siRNA Delivery In Vitro. 2.3 The Use of SWCNTs for siRNA Delivery In Vivo2.4 The Application of CNTs to Hard-to-Transfect-Cells; 2.5 Summary and Perspectives; References; 3 Carbon Nanotubes as a DNA Delivery Agent for Generation of Genetically Modified Mammals Embryos; Abstract; 3.1 Introduction; 3.1.1 Oocyte and Embryo Structures; 3.1.2 Applications of Genetically Modified Animals (GMA); 3.2 Conventional Gene Transfer Methods for Generating Transgenic Animals; 3.2.1 Pronuclear Microinjection; 3.2.2 Embryonic Stem Cell Transgenesis; 3.2.3 Sperm-Mediated Gene Transfer (SMGT); 3.2.4 Retroviral Vectors. 3.2.5 Somatic Cell Nuclear Transfer (SCNT)3.2.6 Zinc-Finger Nucleases (ZFN) and Transcription Activator-like Effector Nucleases (TALENs); 3.3 Carbon Nanotubes (CNT) as a Gene Transfer Agent; 3.3.1 Interaction of CNT and DNA; 3.3.2 Contribution of CNTs to Conventional Techniques; 3.3.3 Potential DNA Delivery to Embryo Without Micromanipulation; 3.4 Genotoxicity; 3.4.1 General Aspects; 3.4.2 Detection Techniques, Toxicity and Genotoxicity of CNTs; 3.5 Summary and Perspectives; References; 4 Development of Carbon Nanotubes-Based Immunogens; Abstract; 4.1 Introduction. 4.2 The Birth of Vaccinology and Current Approaches to Vaccines4.2.1 Inactivated and Subunit Vaccines; 4.2.2 Attenuated Vaccines; 4.3 Alternative Vaccine Design (Thinking Outside the Box): Antigen Delivery and the Use on Nanomaterials; 4.4 Carbon Nanotube-Based Immunogens; 4.4.1 CNTs Immunogenic Properties; 4.4.2 CNTs as Adjuvants in Vaccines; 4.4.3 CNTs Penetration in Cellular Membranes; 4.4.4 CNT-Based Experimental Vaccines; References; 5 Fullerene-Derivatives as Therapeutic Agents in Respiratory System and Neurodegenerative Disorders; Abstract; 5.1 Introduction. 5.1.1 Oxidative Stress and Disease Development5.1.2 Fullerenes Chemical Properties; 5.1.3 Antioxidative Properties of Fullerenes; 5.2 Fullerene-Based Materials as Neuroprotective Agents; 5.3 Fullerene-Based Therapeutics in Respiratory System; 5.3.1 Reactive Oxygen Species in the Lungs; 5.3.2 Fullerene-Based Materials and the Respiratory System; 5.4 Summary and Perspectives; References; 6 Study of Carbon Nanostructures for Soil Fertility Improvement; Abstract; 6.1 Introduction; 6.1.1 Soil Amelioration and Carbon Storage; 6.1.2 Tropical Region and a Sustainable Model. English. |
| Physical Description: |
1 online resource (x, 163 pages) : illustrations (some color). |
| Bibliography: |
Includes bibliographical references. |
| ISBN: |
9783319259079 3319259075 |