Molecular structures and structural dynamics of prion proteins and prions mechanism underlying the resistance to prion diseases /
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions.℗ℓ It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC)...
| Main Author: | Zhang, Jiapu, |
|---|---|
| Other Authors: | SpringerLink (Online service) |
| Format: | eBook |
| Language: | English |
| Published: |
Dordrecht :
Springer,
[2015]
|
| Physical Description: |
1 online resource. |
| Series: |
Focus on structural biology ;
9. |
| Subjects: |
Table of Contents:
- Basic Knowledge
- The Homology Structure and Dynamics
- The NMR Structure and Dynamics of the Wild-type and Mutants
- Compared with the NMR Structure and Dynamics of Humans and Mice
- Compared with the NMR Structure and Dynamics of Dogs and Horses
- Compared with a Homology Structure and Dynamics of Buffaloes
- Compared with NMR Structure and Dynamics of Elks
- Compared with the X-ray Structure and Dynamics of Rabbits
- Surface Electrostatic Charge Distributions
- The Hydrophobic Region PrP(109-136)
- The Hybrid Method of Steepest Descent
- Conjugate Gradient with Simulated Annealing
- Hybrid Method of Discrete Gradient with Simulated Annealing or Genetic Algorithm
- A Novel Canonical Dual Global Optimization Computational Approach
- The Hybrid Method of Evolutionary Computations with Simulated Annealing
- Simulated Annealing Refined Replica Exchange Global Search Algorithm
- LBFGS Quasi-Newtonian Methods for MM Prion AGAAAAGA Amyloid Fibrils
- Particle Swarm Global Optimization Search Algorithm
- A Summary of the Research Works on AGAAAAGA.