Jak-Stat signaling from basics to disease /
JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentia...
| Other Authors: | Decker, Thomas (Professor), Müller, Mathias, 1960-, SpringerLink (Online service) |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Vienna ; New York :
Springer,
©2012.
Vienna ; New York : [2012] |
| Physical Description: |
1 online resource : illustrations. |
| Subjects: |
Table of Contents:
- The Continuing Fascination with Jaks and Stats: An Introduction /
- Thomas Decker and Mathias Müller
- Regulation of JAKs: Insights Gleaned from the Functional Protein Domains /
- Claude Haan, Daniela Ungureanu, Tuija Pekkala, Olli Silvennoinen and Serge Haan
- Nuclear Functions of the Janus Kinases /
- Mark A. Dawson and Andrew J. Bannister
- Self-association of STAT Proteins from Monomers to Paracrystals /
- Mathias Droescher and Uwe Vinkemeier
- How Stats Interact with the Molecular Machinery of Transcriptional Activation /
- Amanda M. Jamieson, Matthias Farlik and Thomas Decker
- Nongenomic Functions of STAT3 /
- Daniel J. Gough, Pravin Sehgal and David E. Levy
- Evolution of Jak and Stat Proteins /
- Claus Vogl, Priyank Shukla and Ingo Ebersberger
- JAK/STAT and Chromatin Regulation in Drosophila /
- Kriti Gaur and Willis X. Li
- JAK/STAT Signaling and Invertebrate Immune Responses /
- Feng Zhou and Hervé Agaisse
- Stat5 as a Hematopoietic Master Regulator for Differentiation and Neoplasia Development /
- Harini Nivarthi, Katrin Friedbichler and Richard Moriggl
- Regulation of Dendritic Cell Development by STATs /
- Haiyan S. Li and Stephanie S. Watowich.
- STAT Transcription Factors: Controlling All Aspects of NK Cell Biology /
- Eva Maria Putz, Eva Zebedin and Veronika Sexl
- Function of JAKs and STATs in Lymphocytes: Bench to Bedside /
- Alejandro Villarino, Xiang-Ping Yang, Kiyoshi Hirahara, Yuka Kanno and John J. O' Shea, et al.
- The Role of Janus Kinases in Hematopoietic Malignancies /
- Damla Olcaydu and Robert Kralovics
- Activation of Janus Kinases During Tumorigenesis /
- Jeffrey W. Schmidt and Kay-Uwe Wagner
- STAT1 and STAT3 Transcription Factors in Inflammation-associated Colon Cancer /
- Paulina Rampetsreiter and Robert Eferl
- Universal and Specific Functions of STAT3 in Solid Tumours /
- Lidia Avalle, Gabriella Regis and Valeria Poli
- Impact of STAT5 on Normal Tissue Development and Cancer /
- Maria M. Caffarel and Christine J. Watson
- Crosstalk with the Jak-STAT Pathway in Inflammation /
- Lionel B. Ivashkiv
- Activation and Inhibition of JAK-STAT Signal Transduction by RNA Viruses /
- Curt M. Horvath
- Multifaceted Antiviral Actions of Interferon-stimulated Gene Products /
- Birgit Strobl, Nicole R. Leitner and Mathias Müller
- Interferon Regulation of the Innate Response to Bacteria /
- Ali Abdul-Sater and Christian Schindler.