Life-span extension single-cell organisms to man /
Many discoveries are made in underlying mechanisms of aging. This book brings together perspectives from researchers investigating aging process in a variety of species. It aims to address aging process in species ranging from yeast to man. It carries discussions of the naked mole-rat, an exceptiona...
| Other Authors: | Sell, Christian., Lorenzini, Antonello., Brown-Borg, Holly M., SpringerLink (Online Service) |
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| Format: | eBook |
| Language: | English |
| Published: |
Totowa, N.J. : London :
Humana ; Springer [distributor],
2009.
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| Physical Description: |
1 online resource (xvii, 198 pages) : illustrations (some color) |
| Series: |
Aging medicine.
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| Subjects: |
| Summary: |
Many discoveries are made in underlying mechanisms of aging. This book brings together perspectives from researchers investigating aging process in a variety of species. It aims to address aging process in species ranging from yeast to man. It carries discussions of the naked mole-rat, an exceptionally long-lived rodent, among other subjects. |
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| Item Description: |
Introduction / Christian Sell -- Part I: Yeast. Reprogramming cell survival and longevity: The role of Tor, Sch9, Ras, and Sir2 / Valter D. Longo -- Part II: Caenorhabditis elegans. Common aging mechanisms: energy metabolism and longevity in Caenorhabditis elegans / Marta Artal-Sanz and Nektarios Tavernarakis ; Conserved mechanisms of life-span regulation and extension in Caenorhabditis elegans / Sean P. Curran -- Part III: Drosophila melanogaster. The genetic architecture of longevity / Robert Arking ; Mild stress and life extension in Drosophila melanogaster / Éric Le Bourg -- Part IV: Rodents. Global food restriction / Michelle E. Matzko, Roger J. McCarter, and Edward J. Masoro ; Growth hormone and aging in mice / Holly M. Brown-Borg, Sunita Sharma, Kurt E. Borg, and Sharlene G. Rakoczy -- Part V: Comparative biology of aging. Exploiting natural variation in life span to evaluate mechanisms of aging / Rochelle Buffenstein ; Slow aging: insights from an exceptionally long-lived rodent, the naked mole-rat / Rochelle Buffenstein and Yael H. Edrey ; Life extension in the short-lived fish Nothobranchius furzeri / Alessandro Cellerino -- Part VI: Aging in humans. Aging and longevity in animal models and humans / Miriam Capri, Stefano Salvioli, Elisa Cevenini, Laura Celani, Federica Sevini, Elena Bellavista, Catia Lanzarini, Stella Lukas, Paolo Tieri, Francesco Lescai, Daniela Monti, and Claudio Franceschi. Many discoveries are made in underlying mechanisms of aging. This book brings together perspectives from researchers investigating aging process in a variety of species. It aims to address aging process in species ranging from yeast to man. It carries discussions of the naked mole-rat, an exceptionally long-lived rodent, among other subjects. Includes bibliographical references and index. University staff and students only. Requires University Computer Account login off-campus. English. |
| Physical Description: |
1 online resource (xvii, 198 pages) : illustrations (some color) |
| Bibliography: |
Includes bibliographical references and index. |
| ISBN: |
9781603275071 160327507X 1282333399 9781282333390 9786612333392 6612333391 |
| Access: |
University staff and students only. Requires University Computer Account login off-campus. |