Published: Humana Press, 2011
Description:
1 online resource (xvi, 332 pages).
Contents:
“…6.6 Nuclear Reprogramming of Human Somatic Cells by Fusion with ES Cells -- 6.7 Selective Chromosome Elimination from Pluripotent Hybrid Cells -- 6.8 Molecular Mechanism of Cell Fusion-Mediated Reprogramming -- 6.9 Perspective -- References -- Chapter 7: Generation of Induced Pluripotent Stem Cells from Somatic Cells -- 7.1 Introduction -- 7.2 Generation of iPS Cells -- 7.2.1 Reprogramming Factors -- 7.2.2 Mouse iPS Cells -- 7.2.3 Human iPS Cells -- 7.2.4 Recent Updates -- 7.3 Safety of iPS Cells -- 7.3.1 Tumorigenicity -- 7.3.2 Myc Family Genes -- 7.3.3 L-Myc and iPS Cells -- 7.4 Generation of iX Cells (X = Any Somatic Cell) -- 7.4.1 History of Direct Conversion (Reprogramming) -- 7.4.2 Induced Neuronal (iN) Cells -- 7.4.3 Induced Cardiomyocyte (iCM) Cells -- 7.4.4 Potential of Directly Reprogrammed iX Cells -- 7.5 Conclusions -- References -- Chapter 8: The Consequences of Reprogramming a Somatic Cell for
Mitochondrial DNA Transmission, Inheritance and Replication -- 8.1 Introduction -- 8.2 The Necessities for Reprogramming the Somatic Nucleus -- 8.3 What Is MtDNA? …”
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