Digital twins applications to the design and optimization of bioprocesses /

This is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into th...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Herwig, Christoph (Editor), Pörtner, Ralf (Editor), Möller, Johannes (Research assistant) (Editor)
Format: eBook
Language:English
Published: Cham, Switzerland : Springer, 2021.
Series:Advances in biochemical engineering/biotechnology ; 177.
Physical Description:
1 online resource (vii, 254 pages) : illustrations (some color).
Subjects:
Biochemical engineering.
Biomedical engineering.
Online Access:SpringerLink - Click here for access
Contents:
  • Potential of model-based design of experiments approaches for bioprocess scale-down
  • Digital Twins and Their Role in Model-Assisted Design of Experiments
  • Digital twins for bioprocess control strategy development and realization
  • The Kalman filter for the supervision of cultivation processes.-The challenge of implementing digital twins in operating value chains
  • Digital twins in the (bio)pharma industry
  • Numerical methods for the design and description of in vitro expansion processes of human mesenchymal stem cells
  • Euler-Lagrangian Simulations: A Proper Tool for Predicting Cellular Performance in Industrial Scale Bioreactors.

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