Theranostic bionanomaterials
Theranostic Bionanomaterials is an invaluable study of recent advances and trends in the development and application of functional bionanomaterials for theranostic applications. This book describes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biol...
| Other Authors: | Cui, Wenguo,, Zhao, Xin, (Ph.D.),, ScienceDirect (Online service) |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Amsterdam :
Elsevier,
[2019]
|
| Physical Description: |
1 online resource : illustrations (some color). |
| Series: |
Micro & nano technologies.
|
| Subjects: |
| Summary: |
Theranostic Bionanomaterials is an invaluable study of recent advances and trends in the development and application of functional bionanomaterials for theranostic applications. This book describes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biological properties and discusses how these functional nanomaterials enable the precise manipulation of architectural, physical and biochemical cell microenvironments in vitro. In addition, it covers how they can act as the carriers of diagnostic or therapeutic agents, thus providing new pathways or strategies for disease diagnosis and treatment. Specific chapters discuss protein delivery, drug delivery, tissue regeneration, bioimaging, biodetection, and much more. This book will be a critical resource for those involved in cutting-edge research in theranostics bionanomaterial.Focuses on nanofabrication methods of bionanomaterialsReviews the application of bionanomaterials, with a focus on drug delivery and diagnosisDescribes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biological properties. |
|---|---|
| Item Description: |
Includes bibliographical references and index. Theranostic Bionanomaterials is an invaluable study of recent advances and trends in the development and application of functional bionanomaterials for theranostic applications. This book describes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biological properties and discusses how these functional nanomaterials enable the precise manipulation of architectural, physical and biochemical cell microenvironments in vitro. In addition, it covers how they can act as the carriers of diagnostic or therapeutic agents, thus providing new pathways or strategies for disease diagnosis and treatment. Specific chapters discuss protein delivery, drug delivery, tissue regeneration, bioimaging, biodetection, and much more. This book will be a critical resource for those involved in cutting-edge research in theranostics bionanomaterial.Focuses on nanofabrication methods of bionanomaterialsReviews the application of bionanomaterials, with a focus on drug delivery and diagnosisDescribes the design and characterization of nanomaterials which exhibit distinctive physical, chemical and biological properties. Front Cover; Theranostic Bionanomaterials; Copyright Page; Contents; List of Contributors; About the Editors; I. Fundamentals of Theranostic Bionanomaterials; 1 Biodistribution, Excretion, and Toxicity of Inorganic Nanoparticles; Abbreviations; 1.1 Introduction: Inorganic Nanoparticles and Their Interest in Medicine; 1.2 Physicochemical Modifications of Inorganic Nanoparticles in Physiological Environments Determine Their Effects: Safety ...; 1.2.1 Effects of the Agglomeration and Aggregation of Nanoparticles; 1.2.2 Effects of the Adsorption of (Macro)Molecules. 1.2.3 Effects of the Corrosion and Degradation of Nanoparticles1.3 Physicochemical Modifications of Inorganic Nanoparticles Determine Their Biodistribution and Fate; 1.3.1 Biodistribution: Nanoparticles Entering the Body; 1.3.2 Subcellular Localization: Nanoparticles Entering the Cells; 1.3.3 Long-Term Effects; 1.4 Outlook and Conclusion; References; 2 Biodistribution, Excretion, and Toxicity of Nanoparticles; 2.1 Introduction; 2.2 Biodistribution; 2.2.1 Effect of Surface Material; 2.2.1.1 PEGylation; 2.2.1.2 Charge; 2.2.2 Effect of Nanoparticle Size; 2.2.3 Effect of Nanoparticle Shape. 2.2.4 Effect of Nanoparticle Rigidity2.2.5 Effect of Administration Route; 2.3 Excretion; 2.3.1 Mononuclear Phagocytic System Clearance; 2.3.2 Renal Clearance; 2.4 Toxicity; 2.4.1 Liver Toxicity; 2.4.2 Kidney Toxicity; 2.4.3 Heart Toxicity; 2.4.4 Brain Toxicity; 2.4.5 Lung Toxicity; 2.5 Challenges and Perspectives; References; 3 Nanoparticle Interaction With Immune Cells for Nanoparticle-Mediated (Anticancer) Immunotherapy; 3.1 Introduction; 3.1.1 Nanoparticles; 3.1.2 Innate Immune System; 3.1.3 Adaptive Immune System; 3.1.4 Immunotherapy. 3.1.5 Nanoparticles as Anticancer Drug-Delivery System3.2 Nanoparticles as Immunotherapy; 3.2.1 Complementing Nanoparticle-Based Therapies; 3.3 Nanoparticles as Vaccines Against Cancer; 3.4 Nanoparticles as Diagnostics; 3.5 Challenges; 3.5.1 Modulating Innate and Adaptive Immunity; 3.5.2 Nanoparticle Characteristics; 3.6 Concluding Remarks; References; 4 Clinical Translation of Nanomaterials; 4.1 Diagnostics; 4.1.1 Carbon Nanotubes; 4.1.2 Nanoparticles; 4.1.3 Quantum Dots; 4.2 Therapeutics; 4.2.1 Polymerics; 4.2.2 Liposomes; 4.3 Tissue Engineering; 4.3.1 Scaffolds; 4.3.2 Hydrogels. 4.4 Conclusion and PerspectiveAcknowledgment; References; 5 Synthetic Receptors With Bioaffinity for Biomedical Applications; 5.1 Introduction; 5.2 Synthetic Receptors for Biomedicines; 5.2.1 Toxin Neutralization; 5.2.2 Bacteria Inhibition; 5.2.3 Biomedical Imaging; 5.2.4 Cancer Therapy; 5.2.5 Cell Isolation; 5.2.6 Other Potentials; 5.3 Conclusion and Perspective; Acknowledgments; References; II. Biomedical Applications of Theranostic Bionanomaterials; I. Drug Delivery and Tissue Engineering; 6 Calcium Phosphate Nanoparticle-Based Systems for Therapeutic Delivery; 6.1 Introduction. |
| Physical Description: |
1 online resource : illustrations (some color). |
| Bibliography: |
Includes bibliographical references and index. |
| ISBN: |
9780128153420 0128153423 |