Treatment of thyroid tumor Japanese clinical guidelines /

Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have es...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Takami, Hiroshi, Ito, Yasuhiro, Dr
Format: eBook
Language:English
Japanese
Published: Tokyo ; New York : Springer, ©2013.
Tokyo ; New York : [2013]
Physical Description:
1 online resource.
Subjects:
Thyroid gland -- Cancer -- Treatment -- Japan.
Online Access:SpringerLink - Click here for access
Contents:
  • Part 1. Epidemiology
  • CQ1. What Are the Risk Factors for Thyroid Cancer?
  • CQ2. Is There a Difference in Prognosis Between Adult Thyroid Cancer and Juvenile Thyroid Cancer or Juvenile Follicular Cancer?
  • Column 1. Genetics of Thyroid Cancer
  • Column 2. Prevalence of Various Histological Types of Thyroid Cancer
  • Column 3. Anaplastic Transformation of Differentiated Carcinoma
  • Column 4. Incidence, Morbidity, and Mortality of Thyroid Carcinoma in Japan.
  • Part 2. Diagnosis and non-surgical management\n
  • CQ3. What Is the Frequency (Probability of Cancer Before Examination) of Thyroid Cancer
  • CQ4. What Are the Factors That Increase the Likelihood of Malignancy and What Is the Odds Ratio and Risk Ratio?
  • CQ5. What Are the Physical Signs and Symptoms That Increase the Likelihood of Thyroid Cancer and What Are the Sensitivity and Specificity?
  • CQ6. What Are the Imaging Studies Most Suitable for the Diagnosis of Thyroid Carcinoma and What Are Their Sensitivity, Specificity, and Likelihood Ratio?
  • CQ7. What Are the Blood Chemistry Data That Increase the Likelihood of Thyroid Malignancy and What Are Their Sensitivity, Specificity, and Likelihood Ratio?
  • CQ8. What Are the Sensitivity and Specificity of Aspiration Cytology?
  • CQ9. What Are the Sensitivity and Specificity of Ultrasonography, CT, MRI, Laryngoscopy, and Bronchoscopy in the Preoperative Evaluation of Thyroid Cancer Invasion to the Trachea, Esophagus, and the Recurrent Laryngeal Nerve?
  • CQ10. How Is the Natural History of Nodules Diagnosed as Benign (Growth and Reduction Rates)?
  • CQ11. Does TSH Suppression Therapy Reduce the Size of Tumors Diagnosed as Benign?
  • CQ12. What Is the Intra-Observer Variation in the Pathological Diagnosis of Follicular Carcinoma?
  • CQ13. What Is the Efficacy of Percutaneous Ethanol Injection Therapy for Autonomously Functioning Thyroid Nodules?
  • CQ14. Do Cystic Nodules Decrease in Volume by Aspiration and Drainage of Content Fluid and Percutaneous Ethanol Injection Therapy?
  • CQ15. What Is the Likelihood That Multinodular Goiter Will Be Surgically Resected After Observation?
  • Column 5. Indication for Surgery of Nodular Goiter
  • Column 6. Diagnosis of Anaplastic Carcinoma.
  • Part 3. Papillary carcinoma
  • CQ16. What Is the Most Appropriate and Convenient Risk Classification System for Predicting the Prognosis of Patients with Papillary Carcinoma?
  • CQ17. Does Total (or Near Total) Thyroidectomy Improve the Prognosis of Papillary Carcinoma Patients Compared to Lobectomy or Lobectomy Isthmectomy?
  • CQ18. Does Central Compartment Dissection Improve the Prognosis of Papillary Carcinoma Patients?
  • CQ19. Does Dissection of the Lateral Compartment Improve the Prognosis of Papillary Carcinoma Patients?
  • CQ20. When Can Papillary Microcarcinoma (Papillary Carcinoma Measuring 1 cm or Less) Be Observed Without Immediate Surgery?
  • Column 7. What Is the Acceptable Incidence for Persistent Recurrent Laryngeal Nerve Paralysis and Persistent Hypoparathyroidism as Complications of Thyroid Surgery?
  • Column 8. The Controversy Regarding the Extent of Thyroidectomy for Papillary Carcinoma and Actual Practice in Japan
  • Column 9. Lobectomy and Paratracheal Node Dissection.
  • Part 4. Follicular tumor
  • Introduction
  • CQ21. Is It Possible to Diagnose Follicular Carcinoma on Preoperative FNA or Intraoperative Frozen Section Diagnosis?
  • CQ22. Does Classification of Follicular Carcinoma According to the Degree of Invasiveness (Widely Invasive and Minimally Invasive Types) Reflect the Prognosis?
  • CQ23. When Is Completion Total Thyroidectomy Recommended as a Second Surgery for Patients Who Underwent Hemithyroidectomy and Were Diagnosed as Having Follicular Carcinoma on Postoperative Pathological Examination?
  • CQ24. Does Total Thyroidectomy with Radioactive Iodine Ablation and TSH Suppression Therapy Improve Patient Prognosis with Widely Invasive Follicular Carcinoma Compared to Only Limited Thyroidectomy?
  • CQ25. Does Prognosis of Oxyphilic (Hurthle Cell) Follicular Carcinoma Differ from That of Conventional Follicular Carcinoma?
  • Part 5. Medullary carcinoma
  • CQ26. What Is the Usefulness of RET Gene Mutation Analysis for Medullary Carcinoma?
  • CQ27. What Are the Incidences of Diseases Associated with Hereditary Medullary Carcinoma?
  • CQ28. Do Total Thyroidectomy and Lymph Node Dissection for Sporadic and Hereditary Medullary Carcinoma Improve the Prognosis?
  • CQ29. Is Chemotherapy Effective for Advanced or Relapsed Medullary Carcinoma?
  • CQ30. What Are Prognostic Factors of Medullary Carcinoma?
  • Part 6. Poorly differentiated carcinoma
  • CQ31. What Is the Definition of Poorly Differentiated Carcinoma? What Is Its Prevalence and Prognosis?
  • CQ32. Can Poorly Differentiated Carcinoma Be Diagnosed Preoperatively?
  • CQ33. Do Total Thyroidectomy and Prophylactic Lymph Node Dissection Improve the Prognosis of Patients with Poorly Differentiated Carcinoma?
  • CQ34. Does Additional Surgery Improve the Prognosis of Patients Who Underwent Hemithyroidectomy Under a Diagnosis of Papillary or Follicular Carcinoma, But Who Are Later Diagnosed as Having Poorly Differentiated Carcinoma on Postoperative Pathological Examination?
  • CQ35. Do Therapies Other Than Surgery Improve the Prognosis for Patients with Poorly Differentiated Carcinoma?
  • Column 10. Carcinoma Showing Thymus-Like Differentiation/Intrathyroidal Epithelial Thymoma.
  • Part 7. Anaplastic carcinoma
  • Introduction
  • CQ36. Does Surgical Treatment for Anaplastic Carcinoma Improve Prognosis?
  • CQ37. Do Adjuvant Therapies Improve the Prognosis of Anaplastic Carcinoma in Patients Who Underwent Curative Surgery?
  • CQ38. Does Combined Modality Therapy for Anaplastic Carcinoma Improve Prognosis?
  • CQ39. Should Relapsed Lesions of Differentiated Carcinoma That Were Diagnosed as Anaplastic Carcinoma Be Treated as Anaplastic Carcinoma?
  • Column 11. When Should Palliative Care Be Considered? Is the Prognosis Explained to Patients?
  • Column 12. Squamous Cell Carcinoma of the Thyroid Is Currently Classified as a Different Histology from Anaplastic Carcinoma. Are Therapeutic Strategies and Prognosis of Squamous Cell Carcinoma Similar to Those of Anaplastic Carcinoma?
  • Part 8. Radiation therapy
  • CQ40. What Are Applications and Roles of Ablation?
  • CQ41. Is Iodine Restriction Necessary Before Ablation?
  • CQ42. What Is the Appropriate Dose of 131I?
  • CQ43. What Is the Benefit of RAI Therapy for Local Recurrence, Lymph Node Metastasis and Distant Metastasis of Differentiated Thyroid Carcinoma?
  • CQ44. What Is the Application, Effect and Safety of Recombinant Human Thyroid Stimulating Hormone (rhTSH)?
  • Column 13. Comments on RAI Therapy Including the Actual Situation in Japan
  • Column 14. Applications for External Beam Radiotherapy for Differentiated Thyroid Carcinoma
  • Column 15. Is it Appropriate to 131I Scintigraphy Before RAI Therapy? What Is the Dose?
  • Column 16. What Is the Actual Status of Radiotherapy (External Beam Radiotherapy and 131I MIBG Therapy)?
  • Column 17. What Are the Side Effects of RAI Therapy and What Is Their Frequency?
  • Part 9. Surgical Treatment for Advanced Differentiated Carcinoma
  • CQ45. What Is the Indication for Resection of the Recurrent Laryngeal Nerve for Cases Extending There?
  • CQ46. Is Phonetic Function Improved by Reconstruction of the Recurrent Laryngeal Nerve?
  • CQ47. For Cases Extending to the Trachea, Does Sleeve Resection of the Trachea Improve the Survival Rate Compared to Partial Resection (Wedge Resection or Window Resection)?
  • CQ48. Does Tracheal Resection Improve the Survival Rate Compared with No Resection?
  • Column 18. Treatment and Management Approaches for Cases Extending to the Trachea with Larynx, Esophagus, or Mediastinum Involvement.
  • Part 10. Postoperative observation of differentiated carcinoma and treatment for inoperable cases
  • CQ49. Does TSH Suppression Therapy After Surgery for Differentiated Thyroid Carcinoma Improve Survival?
  • CQ50. Is Serum Thyroglobulin Measurement Useful as a Marker of Carcinoma Recurrence After Surgery?
  • CQ51. Are Measurements of Calcitonin and CEA Useful as Markers of Recurrence After Surgery for Medullary Carcinoma?
  • CQ52. What Are Useful Imaging Studies to Detect Lesions of Recurrence for Medullary Carcinoma with Elevation of Postoperative Calcitonin Level?
  • CQ53. Is Chemotherapy for Advanced Thyroid Carcinoma Effective?
  • CQ54. Is Percutaneous Ethanol Injection Therapy Effective for Local or Lymph Node Recurrence and Bone Metastasis?
  • CQ55. Are Alternate Therapies Effective for Thyroid Carcinoma?
  • Column 19. How Long Should Patients with Differentiated Thyroid Carcinoma Be Followed After Surgery?

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