Phosphodiesterases as drug targets

Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that...

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Other Authors: Francis, Sharron H., Conti, Marco, Prof., Houslay, Miles D., SpringerLink (Online service)
Format: eBook
Language: English
Published: Berlin ; New York : Springer, ©2011.
Berlin ; New York : [2011]
Physical Description: 1 online resource (xvii, 519 pages).
Series: Handbook of experimental pharmacology ; v. 204.
Subjects:

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