Sphingolipids as signaling and regulatory molecules
This book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation, and infectious disea...
| Other Authors: | Chalfant, Charles, 1970-, Del Poeta, Maurizio., SpringerLink (Online service) |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, N.Y. : Austin, Tex. :
Springer Science+Business Media ; Landes Bioscience,
©2010.
New York, N.Y. : Austin, Tex. : [2010] |
| Physical Description: |
1 online resource (xxv, 291 pages) : illustrations (some color). |
| Series: |
Advances in experimental medicine and biology ;
v. 688. |
| Subjects: |
| Summary: |
This book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation, and infectious diseases. |
|---|---|
| Item Description: |
Includes bibliographical references and index. An overview of sphingolipid metabolism : from synthesis to breakdown / Christopher R. Gault, Lina M. Obeid and Yusuf A. Hannun -- Sphingolipid transport / Laura Riboni, Paola Giussani and Paola Viani -- Sphingolipid analysis by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) / Jacek Bielawski [and others] -- Ceramide synthases : roles in cell physiology and signaling / Johnny Stiban, Rotem Tidhar and Anthony H. Futerman -- Tales and mysteries of the enigmatic sphingomyelin synthase family / Joost C.M. Holthuis and Chiara Luberto -- Ceramide in stress response / Mariana N. Nikolova-Karakashian and Krassimira A. Rozenova -- Animal models for studying the pathophysiology of ceramide / Toshihiko Kawamori -- Ceramide-1-phosphate in cell survival and inflammatory signaling / Antonio Gómez-Muñoz [and others] -- Ceramide-1-phosphate in phagocytosis and calcium homeostasis / Vania Hinkovska-Galcheva and James A. Shayman -- Extracellular and intracellular actions of sphingosine-1-phosphate / Graham M. Strub [and others] -- Glucosylceramide in humans / Maria C. Messner and Myles C. Cabot -- Gangliosides as regulators of cell membrane organization and functions / Sandro Sonnino and Alessandro Prinetti -- Cancer treatment strategies targeting sphingolipid metabolism / Babak Oskouian and Julie D. Saba -- Therapeutic strategies for diabetes and complications : a role for sphingolipids? / Todd E. Fox and Mark Kester -- Roles for sphingolipids in saccharomyces cerevisiae / Robert C. Dickson -- Sphingolipid signaling in fungal pathogens / Ryan Rhome and Maurizio Del Poeta -- Sphingolipids in parasitic protozoa / Kai Zhang, James D. Bangs and Stephen M. Beverley -- Biosynthesis of sphingolipids in plants (and some of their functions) / Simone Zäuner, Philipp Ternes and Dirk Warnecke -- Computational analysis of sphingolipid pathway systems / Eberhard O. Voit, Fernando Alvarez-Vasquez and Yusuf A. Hannun -- Appendix: Introduction to tools and techniques for ceramide-centered research / Kazuyuki Kitatani and Chiara Luberto. This book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation, and infectious diseases. |
| Physical Description: |
1 online resource (xxv, 291 pages) : illustrations (some color). |
| Bibliography: |
Includes bibliographical references and index. |
| ISBN: |
9781441967411 1441967419 1283074524 9781283074520 |