Phosphoinositide 3-kinase in health and disease Volume 2 /
PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impact of intervention with PI3K activity are high, and progress in the clinical arena is being monitored by many. However, targeted therapies almost inva...
| Other Authors: | Rommel, Christian., Vanhaesebroeck, Bart., Vogt, P. K. 1932-, SpringerLink (Online service) |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Berlin ; Heidelberg :
Springer,
©2011.
Berlin ; Heidelberg : [2011] |
| Physical Description: |
1 online resource (x, 304 pages) : illustrations. |
| Series: |
Current topics in microbiology and immunology ;
v. 347. |
| Subjects: |
Table of Contents:
- 880-01
- Phosphoinositide 3-kinase in Health and Disease; Volume 2; Contents; Contributors; PI3K: From the Bench to the Clinic and Back; Oncogenic Mutations of PIK3CA in Human Cancers; Structural Effects of Oncogenic PI3Ka Mutations; Comparing the Roles of the p110a and p110beta Isoforms of PI3K in Signaling and Cancer; Phosphatidylinositol 3-Kinase: The Oncoprotein; AKT Signaling in Physiology and Disease; Faithfull Modeling of PTEN Loss Driven Diseases in the Mouse; PI3K as a Target for Therapy in Haematological Malignancies; Clinical Development of Phosphatidylinositol-3 Kinase Pathway Inhibitors.